https://www.smanskilab.tech/index daily 0.75 2019-07-01 https://www.smanskilab.tech/welcome-pacific daily 1.0 2026-03-19 https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562156695946-Q20B1JX3UBKJQLQ949B5/Biology-inspired-3.png Welcome https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/e8277aaa-d266-41b3-8cc4-46d107a47621/mitppc.png Welcome - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562160361135-L81IBLT03XTSO78D1DR1/applications.png Welcome https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562015079867-2O8MFLBYTMNQQ9OP7SL6/tech.png Welcome https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562015153448-35JA87UNB7YYFKP5GEYA/genDesignOpt.png Welcome - 1. Genetic Design Optimization Living organisms build the most complex and useful chemicals known to man. We use novel engineering strategies to re-write the genetics of natural product biosynthesis. We apply this to discover and over-produce molecules from nature that have applications as drugs, pesticides, and herbicides. https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562015441628-1A5O5N8XZOLHHCKXRELS/synthSp.png Welcome - 2. Engineered Speciation Species boundaries are defined by pre-zygotic and post-zygotic barriers to genetic exchange. By engineering such barriers, we can essentially create ‘new’ species. We apply this technology to limit the gene flow between populations and as a mechanism to control or eradicate pest organisms. Synthetic species can also be used as drivers of evolution in competitive co-cultures. https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562015515931-4ZOFZYHTYDRI261CDU2D/complexSystems.png Welcome - 3. Complex Systems Engineering Since the advent of recombinant DNA technology in the early 1970’s, most biotechnology applications are comprised of relatively simple, single-gene systems. We are leveraging advances in algorithmic DNA assembly to design, build, and test large, multi-gene systems with applications in medicine, agriculture, and the environment. https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/84b995e3-76fb-43ce-a7c5-299703e7333e/Julie_crop.png Welcome - Make it stand out Julie Badger Graduate Student beenk006@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/a026badd-6e72-4a61-a39f-2e7bdcac37ac/Savio_de_Siqueira_Ferreira_crop.png Welcome - Make it stand out Savio De Siqueira Ferreira Postdoctoral Scholar sdesique@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/4f1a00ad-9043-4116-8b53-2757d368831e/Ratnasri_Pothula_crop.png Welcome - Make it stand out Ratnasri Pothula Postdoctoral Scholar ratnasri@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/ab5dd8c2-a3e9-4dc4-98fa-7944af46162a/Nate_Feltman_crop.png Welcome Nate Feltman Postdoctoral Scholar feltm006@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/2a190c6b-0bdd-4dce-8233-8193664cc2bc/Leland_crop.png Welcome - Make it stand out Leland Feist Graduate Student lfeist@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/22603c2f-1f2b-4766-ba32-679db8e9dad4/Collin.png Welcome - Make it stand out Collin Woolson Technician wools043@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/71d91289-6531-47e8-9f01-bbec262fd2ed/Maxime_Boneza_crop.png Welcome Maxime Boneza Graduate Student bonez001@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/9b9ccaf9-ecf6-4296-9ad7-32c900f586c7/Colby_crop.png Welcome - Make it stand out Colby Johnson Graduate Student joh15243@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/ae07c35a-f140-41d5-874c-fba5c3f91cae/jacob.jpg Welcome - Make it stand out Jacob Kracke-Bock Graduate Student krack008@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/68107296-d6ab-4ae0-a73f-184fcaf49935/Jonathan_Cors_crop.png Welcome Jonathan Cors Graduate Student corsx006@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/d6c0fb24-d852-4c44-a14d-5721fa99563c/Seonyun_Moon_crop.png Welcome Seonyun Moon Graduate Student moon0215@umn.edu https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1598913705898-9AH1F1R9R82TM69SFI6W/mike.png Welcome Michael Smanski Group Leader smanski@umn.edu https://www.smanskilab.tech/home daily 0.75 2019-07-01 https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562005835346-5ELZUPNGRP3O4F5UMO4Q/Biology-inspired.png Home https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562006729817-YDRTVX19UZDP4XAIWOTS/tech.png Home https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562007241262-5MW81A2Y0Y7PMG6842MU/synthSp.png Home https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562006895114-WGUMTG3VDU6G0XLW6WMW/genDesignOpt.png Home https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562007612770-PQJABPMB6KIXN2I0ZFK9/complexSystems.png Home https://images.squarespace-cdn.com/content/v1/5d1a45ae73ef2f00014ae2ef/1562012074499-BGOWS8Y1RTY7TRZHGU8Y/applications.png Home https://www.smanskilab.tech/what-we-do daily 0.75 2014-01-16 https://images.squarespace-cdn.com/content/v1/52a74d9ae4b0253945d2aee9/1390513380961-PTHFXE5U2S1FJSLPXUSD/tumblr_mh1iruZWLf1rkz363o1_1280.jpg What We Do